ZYMOBACTER PALMAE PYRUVATE DECARBOXYLASE IS LESS EFFECTIVE THAN THAT OF ZYMOMONAS MOBILIS FOR ETHANOL PRODUCTION IN METABOLICALLY ENGINEERED SYNECHOCYSTIS SP. PCC6803

Zymobacter palmae Pyruvate Decarboxylase is Less Effective Than That of Zymomonas mobilis for Ethanol Production in Metabolically Engineered Synechocystis sp. PCC6803

To produce bioethanol from model cyanobacteria such as Synechocystis, a two gene cassette consisting of genes encoding pyruvate decarboxylase (PDC) and alcohol dehydrogenase (ADH) are required to transform pyruvate first to acetaldehyde and then to ethanol.However the partition of pyruvate to ethanol comes at a cost, a reduction in biomass and pyru

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Cancer Genetic Network Inference Using Gaussian Graphical Models

The Cancer Genome Atlas (TCGA) provides a rich resource that can be used to understand how genes interact in cancer cells and has collected RNA-Seq gene expression data for many types of human cancer.However, mining the data to uncover the hidden gene-interaction patterns remains a challenge.Gaussian graphical model (GGM) is often used to learn gen

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